Design, Fabrication and Evaluation of Ketorolac Tromethamine Loaded Microsponge Based Colon Targeted Tablet
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چکیده
منابع مشابه
Formulation and Evaluation of Mouth Dissolving Tablet of Ketorolac Tromethamine for Pain Management by Using Superdisintegrants
s: Mouth dissolving tablet is the fast growing and highly accepted drug delivery system. This study was aimed at development of Ketorolac Tromethamine mouth dissolving tablet, which can disintegrate or dissolve rapidly once placed in the oral cavity. Conventional Ketorolac tromethamine tablet require water to swallow it and have disadvantages like low disintegration rate, low solubility etc.Ket...
متن کاملIn-vitro Release Characterization of Ketorolac Tromethamine Loaded Matrix Tablets
The present investigation highlighted the formulation and release characterization of Ketorolac Tromethamine loaded matrix tablet. Various formulations of tablets were prepared by direct compression method along with Kollidon SR and Hydroxy Propyl Methyl Cellulose (HPMC) as release retardant polymers. Each of the formulated tablets contains 50mg Ketorolac Tromethamine. The evaluation involved p...
متن کاملDesign and Characterization of Transdermal films containing Ketorolac tromethamine
1. Abstract: The objective of this work was to develop suitable film formulations of ketorolac tromethamine (KT) for transdermal use and to investigate the effect of film composition and permeation enhancers on the in-vitro release and skin permeation of the drug. Polyvinyl alcohol (PVA), sodium carboxymethylcellulose (NaCMC), and chitosan were used as film-forming polymers. The adhesive hydrop...
متن کاملDevelopment of Microparticle Loaded Gel (MPLGs) for Prolong Ocular Drug Delivery Containing Ketorolac Tromethamine
Microparticles loaded gels (MPLGs) are colloidal drug carriers in the microand submicron range. These systems were developed to overcome solubility problems of poorly soluble drugs as well as for long acting injectable depot formulations and specific drug targeting options. The main objective for these systems was to improve the classical aqueous eye drop formulations which have major disadvant...
متن کاملFabrication and Evaluation of Ketorolac Loaded Cubosome for Ocular Drug Delivery
Article history: Received on: 14/05/2016 Revised on: 09/06/2016 Accepted on: 24/06/2016 Available online: 26/09/2016 Ophthalmic formulations in terms of eye drops are more frequently used formulation for ocular disorders. But unfortunately this mode of drug instillation into the cul-de-sac of eye shows very poor ocular bioavailability (less than 5%). A large number of carrier systems have been ...
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ژورنال
عنوان ژورنال: International Journal of Advances in Pharmacy and Biotechnology
سال: 2020
ISSN: 2454-8375
DOI: 10.38111/ijapb.20200602002